Choosing the Right Weight Loss Medication: Wegovy vs. Saxenda vs. Mounjaro
With several prescription medications now available to support weight loss, it can be difficult to know which option is best for your needs. While all three—Wegovy, Saxenda, and Mounjaro—have shown impressive results, they differ in how they work, how often they’re taken, and who they’re approved for.
Below is a side-by-side comparison to help you understand the key differences between these popular weight loss treatments. This chart highlights how each medication works, their dosing schedules, weight loss potential, and more—so you can make an informed decision in consultation with your healthcare provider.
Comparison: Wegovy vs. Saxenda vs. Mounjaro
|
Feature |
Wegovy |
Saxenda |
Mounjaro |
|
Generic Name |
Semaglutide |
Liraglutide |
Tirzepatide |
|
FDA-Approved For |
Weight management |
Weight management |
Type 2 diabetes (weight loss off-label) |
|
Mechanism of Action |
GLP-1 receptor agonist |
GLP-1 receptor agonist |
Dual GIP & GLP-1 receptor agonist |
|
Dosing Frequency |
Once weekly |
Once daily |
Once weekly |
|
Delivery Form |
Prefilled injection pen |
Prefilled injection pen |
Prefilled injection pen |
|
Starting Dose |
0.25 mg weekly (titration) |
0.6 mg daily (titration) |
2.5 mg weekly (titration) |
|
Typical Maintenance Dose |
2.4 mg weekly |
3.0 mg daily |
5–15 mg weekly |
|
Weight Loss Potential |
Up to 15% or more (studies) |
~5–10% (studies) |
Up to 22% (off-label studies) |
|
Approved For Obesity |
✅ Yes |
✅ Yes |
❌ No (used off-label) |
|
Common Side Effects |
Nausea, vomiting, constipation |
Nausea, diarrhea, headache |
Nausea, decreased appetite |
|
Ease of Use |
Weekly, easy to follow |
Daily, more commitment needed |
Weekly, easy to follow |
|
Available At |
|||
|
Support Line |
1-800-214-7456 |
1-800-214-7456 |
1-800-214-7456 |
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